Viagra, Cialis???
- Thread starter canthelpit
- Start date
with Covid.
I randomly provided the information as I felt it was appropriate because it has worked for me, both the price and the venue/process. I do not believe I went into a price tangent per say as retail estimates and retail prices might change without notice. I only read the most current comments and added from there. With respect to the symptoms, I don’t usually get any if I maintain the recommended dose (3 or less) or take it on a full stomach. If I take more than four or on a limited diet, or did not eat regularly that day—I get a running nose or a headache.
Grapefruit juice with V or C is a double edged sword; it increases the blood level concentration but it also increase the time it takes to get to the peak.
It also contains substances which interfere with liver enzymes that break down the medication so the effect of V and C will last longer. The problem is the effects may vary greatly based on the particular sample of juice used.
Note that there are other drugs that are affected this way, statins come to mind, so it can be dangerous to take a daily medication when you also take grapefruit juice every day as the medication blood level will build up as the liver will be prevented to metabolize them.
It also contains substances which interfere with liver enzymes that break down the medication so the effect of V and C will last longer. The problem is the effects may vary greatly based on the particular sample of juice used.
Note that there are other drugs that are affected this way, statins come to mind, so it can be dangerous to take a daily medication when you also take grapefruit juice every day as the medication blood level will build up as the liver will be prevented to metabolize them.
My best guess is that the effects will also vary by person.
So only way to know is self-experimentation and keeping track of time/dose/other factors.
I do see something similar on interactions with coffee and NSAID. I read online that the pain relievers could be more effective taken with caffeine and personal use with coffee seems to be consistent.
So only way to know is self-experimentation and keeping track of time/dose/other factors.
I do see something similar on interactions with coffee and NSAID. I read online that the pain relievers could be more effective taken with caffeine and personal use with coffee seems to be consistent.
And a very good guess I might add.
For example for sildenafil, data comparisons between Middle Eastern and other ethnicities indicated that Iranian, Mexican, and Thai would potentially have twice the effect observed in Arabs and Caucasians, considering the same prescribed drug formulation and dose.
Yup, which is why I pick up a McD's senior coffee on my way to Flushing. Cute manager there even recognizes me as I'm there every Sunday am, and my coffee is ready just as she dumps my exact change w/o counting it into register. (97¢ and IMHO better than Dunkin — in fact I switched my pour over home brew from Gevalia to McCafe medium roast that I found at some market)
For example for sildenafil, data comparisons between Middle Eastern and other ethnicities indicated that Iranian, Mexican, and Thai would potentially have twice the effect observed in Arabs and Caucasians, considering the same prescribed drug formulation and dose.
Yup, which is why I pick up a McD's senior coffee on my way to Flushing. Cute manager there even recognizes me as I'm there every Sunday am, and my coffee is ready just as she dumps my exact change w/o counting it into register. (97¢ and IMHO better than Dunkin — in fact I switched my pour over home brew from Gevalia to McCafe medium roast that I found at some market)